The ELSA-TSHNN kit enables an accurate and specific measurement of the TSH in the first days of life for newborns. The excellent analytical sensibility, 1.5 ?IU/mL, and the reliability of the assay enable very good diagnosis of congenital hyperthyroidism.
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Congenital hypothyroidism neonatal screening (TSH-NN) immunoradiometric assay kit
Features
- Working range: 0 ? 400 ?IU/mL (1st ISNS-RPNS)
- Sample: dried blood spot on paper disks
- Analytical sensitivity: 1.5 ?IU/mL
Applications
- Screening for neonatal congenital hypothyroidism
- High incidence in pediatrics (about 1 case out of 3,600 births)
- Screening can mean the prevention of irreversible effects, by thyroid replacement therapy within postnatal weeks of life
Assay principle
IRMA
Solid phase ELSA system
Two monoclonal anti-hTSH antibodies are used in the sandwich. The first monoclonal antibody is coated on the ELSA solid phase. The second monoclonal antibody, radiolabeled with iodine-125, is used as the tracer.
*One-step assay procedure: 20 h RT.