Cisbio Bioassays offers an accurate immunoradiometric assay for T4. The assay is based on the competition type principle and is carried out in serum. The short 45 minute incubation enables results to be obtained very quickly. The reliability of the results leads to a precise differential diagnosis between neurovegetative dystonia and hyperthyroidism.
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- T4 RIA
L-Thyroxine (T4) radioimmunoassay kit
Features
- Working range: 0 ? 360 ng/mL (461 nmol/L)
- Sample: serum or plasma ? 20 ?L
- Analytical sensitivity: 2.5 ng/mL (3.2 nmol/L)
Applications
- Differential diagnosis between neurovegetative dystonia and hyperthyroidism
- In suspected hypothyroidism, as in suspected hyperthyreosis (Morbus Basedow and adenomas of the thyroid) in goitre
- For therapy surveillance in substitution by thyroxine and in thyreostatic therapy
Assay principle
RIA
Coated tubes
The principle of the assay is based on competition between 125iodine radiolabeled T4 and T4 contained in the samples for a fixed and limited number of anti-T4 polyclonal antibody binding sites adsorbed onto the tube walls.
*One-step assay procedure: 45 minutes at RT / shaking.