The VGK/25 kit is used for the quantitative determination of VGKC autoantibodies Cisbio Bioassays offers an accurate immunoradiometric assay for measuring the Voltage-gated potassium channel (VGKC) autoantibodies. It is carried out in human serum.
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- VGKCAb RIA
Voltage-gated potassium channel (VGKC) autoantibody RIA kit assay
Features
- Working range: 1 negative control and 2 positive controls
- Sample: serum and plasma; 50 ?L
- Analytical sensitivity: 4.5 pmol/L
Applications
- Voltage-Gated Potassium Channelopathies
- Neurological disorders such as neuromyotonia (NMT), cramp-fasciculation syndrome (CFS) and disorders of the central nervous system including Morvan Syndrome, epilepsy and encephalitis
Assay principle
RIP
Immunoprecipitating reagent
The sample containing VGKC Ab is incubated with 125I-VGKC. After the addition of Antihuman IgG and centrifugation, the precipitate is counted.
*Assay procedure: 16 h to 20 h at RT + 90 min RT + 20 min RT (centrifugation).