Procollagen-III-peptide ELISA assay The P3NP-ELISA test enables the determination of human procollagen III peptide. It is based on the principle of a very easy to use sandwich assay. The 30 ?l blood sample is convenient for patients. The transformation of functioning liver tissue into connective tissue is detectable through a raised serum procollagen III peptide level. This is the case, for instance, in alcoholic or virus induced forms of liver fibrosis. The parameter is suitable for monitoring the course of liver disorders and particularly in psoriatic patients treated by Methotrexate. The procollagen III peptide determination enables to reduce the number of biopsy for a better patient comfort and cost savings. Procollagen III N-terminal Propeptide (P3NP) is synthetized in fibroblasts and released from the precursor peptide during the synthesis and deposition of Type III Collagen. Related product: HYAL-ELISA ( Hyaluronic acid ELISA assay)