상정인터내셔널(주) SANG CHUNG INTERNATIONAL Co.,Ltd.

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Congenital hypothyroidism neonatal screening (TSH-NN) immunoradiometric assay kit

The ELSA-TSHNN kit enables an accurate and specific measurement of the TSH in the first days of life for newborns. The excellent analytical sensibility, 1.5 ?IU/mL, and the reliability of the assay enable very good diagnosis of congenital hyperthyroidism.

Features

  • Working range: 0 ? 400 ?IU/mL (1st ISNS-RPNS)
  • Sample: dried blood spot on paper disks
  • Analytical sensitivity: 1.5 ?IU/mL

Applications

  • Screening for neonatal congenital hypothyroidism
  • High incidence in pediatrics (about 1 case out of 3,600 births)
  • Screening can mean the prevention of irreversible effects, by thyroid replacement therapy within postnatal weeks of life
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Ref: ELSA-TSH-NN

작용원리

IRMA

Solid phase ELSA system

두개의 단일클론성 anti-hTSH 항체는 샌드위치법에 사용된다.
첫번째 단일클론성 항체는 ELSA의 고체상에 코팅이 되어있고, Iodine 125가 표지된 두번째 단일클론성 항체는 추적자로 사용된다.
*1 step 검사 절차: RT(실온)에서 20시간.

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