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Thyroxine Binding Globulin (TBG) radioimmunological assay kit

Cisbio Bioassays offers an accurate immunoradiometric assay for thyroxine binding protein (TBG). The assay is based on the competition type principle. The short 30 minute incubation enables results to be obtained very quickly. Added to the dosage of T4, the TBG assay enables the calculation of the T4/TBG ratio, key to a differential diagnosis between hypothyroidism, euthyroidism and hyperthyroidism.

Features

  • Working range: 0 ? 80 ?g/mL
  • Sample: serum or plasma ? 20 ?L

Applications

  • Assessment of the thyroid function
  • T4/TBG ratio: differential diagnosis for euthyroid, hypothyroid, hyperthyroid metabolic status
  • TBG alone: diagnosis of congenital TBG anomalies
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Ref: OCRU03-TBG

작용원리

RIP

PEG

혈청 TBG는 특정 항 TBG 항체에서 제한된 수의 결합 부위에서 125I-TBG 추적기와 경쟁한다. Free TBG는 PEG(Polyethylene 글리콜)로 후자를 촉진시켜 TBG-antibody 복합체로부터 분리된다. 침전물의 Iodine 125 방사능량이 측정된다.
*2 step 검사 절차: RT(실온)에서 30분 + 20분간 원심분리.

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