The only patented * assay targeting the core of the molecule (145-245), Cisbio’s Chromoa R assay offers exceptional sensitivity, specificity, and reproducibility by using two monoclonal antibodies to measure intact and fragmented Chromogranin A (CgA).This enhances the reliability of results. Chromogranin A measurements in neuroendocrine tumors are established in the guidelines** as an aid for diagnosis, treatment efficiency and prognostic factors. Developed under a sandwich-type ELISA format, Chromoa R is simple to use and can be easily adapted to automated systems for implementation in laboratories of all sizes. *EP1078266,US 6,632,624 ** Guidelines
- Home
- 제품소개
- In-Vitro Diagnostics
- Oncology
- CgA ELISA
Chromogranin A ELISA kit
Features
- Working range: 7 ? 820 ng/mL
- Sample: serum or plasma ? 20 ?L
- Analytical sensitivity: 7 ng/mL
- Functional sensitivity: 11 ng/mL
Applications
- High specificity and sensitivity in tumors of neuroendocrine origin
- Diagnosis and follow-up in pheochromocytoma, gastrinoma, carcinoid tumors
- Adverse prognostic factor in prostate cancer
작용원리
ELISA
Microplate
두개의 단일클론성항체는 샌드위치법에 사용된다.
첫번째 단일클론성 항체는 마이크로플레이트에 고정되어 있고, 두번째 단일클론성 항체는 Horse-Radish-Peroxidase에 결합된다.
*두가지 검사 절차: 표준절차(RT(실온)에서 16시간 + RT(실온)에서 2시간 / Shaking + RT(실온)에서 10분 / Shaking) 또는 급속절차(RT(실온)에서 2시간 / Shaking + RT(실온)에서 2시간 / Shaking + RT(실온)에서 10분 / Shaking)