The TR-AB-CT kit is used for the quantitative determination of TR-AB-CT autoantibodies in human serum. Cisbio Bioassays offers an accurate immunoradiometric (RIA) assay for measuring the receptor autoantibody autoantibodies (TRAb). It is based on the competition type principle and carried out in human serum.
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- TRAb RIA
TSH receptor autoantibody (TRAb) radioimmunoassay kit
Features
- Working range: 0.33 ? 40 U/L (1st IS 90/672)
- Sample: serum ? 100 ?L
- Analytical sensitivity: 0.3 U/L
- Functional sensitivity: 0.8 U/L
Applications
- Indication in Graves’ disease
- Prognostic value after treatments: antithyroid drug therapy or after thyroidectomy
- Detection of hyperthyroidism of newborns whose mothers suffer from Graves’ disease
- Presence of TRAb in certain cases of Hashimoto’s thyroiditis, subacute thyroiditis or silent thyroiditis in thyrotoxicosis phase
작용원리
RIA
Coated tubes
Iodine 125가 표지된 TSH와 튜브 벽에 흡착된 TSH 수용체가 들어 있는 샘플의 anti-TSH 수용체 자기항체(TRAb) 간의 경쟁반응에 기초한다.
*2 step 검사 절차: RT(실온)에서 2시간 / Shaking + RT(실온)에서 60분 / Shaking.