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P-Type Voltage-Gated Calcium Channel (VGCC) Autoantibody RIA kit assay

Cisbio offers a accurate immunoradiometric assay for measuring the P-Type Voltage-Gated Calcium Channel (VGCC) autoantibodies. It is carried out in human serum.

Features

  • Measurement range: 1 negative control et 1 positive control
  • Sample: serum: 25 ?L
  • Analytical limit detection: 2,86 pmol/L

Applications

  • P-Type Voltage-Gated Calcium Channel (VGCC) channelopathies
  • Neurological disorders such as Lambert-Eaton myasthenic syndrome (LEMS)
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작용원리

RIP

R?actif immunoprecipitant

VGCC Ab가 포함된 샘플을 Iodine 125가 표지된 VGCC(추적자)와 같이 배양한다. Antihuman IgG을 첨가하고 원심분리 후, 침전물의 방사능량을 측정한다.
*검사 절차: RT(실온)에서 1시간 + RT(실온)에서 20분간 원심분리.

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