The VGK/25 kit is used for the quantitative determination of VGKC autoantibodies Cisbio Bioassays offers an accurate immunoradiometric assay for measuring the Voltage-gated potassium channel (VGKC) autoantibodies. It is carried out in human serum.
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- VGKCAb RIA
Voltage-gated potassium channel (VGKC) autoantibody RIA kit assay
Features
- Working range: 1 negative control and 2 positive controls
- Sample: serum and plasma; 50 ?L
- Analytical sensitivity: 4.5 pmol/L
Applications
- Voltage-Gated Potassium Channelopathies
- Neurological disorders such as neuromyotonia (NMT), cramp-fasciculation syndrome (CFS) and disorders of the central nervous system including Morvan Syndrome, epilepsy and encephalitis
작용원리
RIP
Immunoprecipitating reagent
VGKC Ab가 포함된 샘플을 Iodine 125가 표지된 VGKC와 같이 배양한다. Antihuman IgG을 첨가하고 원심분리 후, 침전물의 방사능량을 측정한다.
*검사 절차: RT(실온)에서 16~20시간 + RT(실온)에서 90분 + RT(실온)에서 20분간 원심분리.